Wearing Down of Protective System in Brain May Underlie Huntington’s

Wearing Down of Protective System in Brain May Underlie Huntington’s

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Wearing Down of Protective System in Brain May Underlie Huntington’s

Progression in Huntington’s disease may be due more to a gradual loss of the system that maintains the health of brain cells than to accumulated damage caused by the disease itself, a computational analysis of large and complex datasets suggests. This analysis, called Geomic, showed that while brain cells most vulnerable to Huntington’s continue to activate a series of compensatory mechanisms to maintain their function and survival in the presence of such damage, these mechanisms eventually wear…

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