Combinations of Variants Contribute to Genetic MS Risk

Combinations of Variants Contribute to Genetic MS Risk

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Combinations of Variants Contribute to Genetic MS Risk

Genetic susceptibility to multiple sclerosis (MS) depends on an individual’s particular combination of multiple risk variants, a study reveals. The study, “Genetic susceptibility to multiple sclerosis: interactions between conserved extended haplotypes of the MHC and other susceptibility regions,” was published in the journal BMC Medical Genomics. The risk of developing MS is thought to be due to a combination of environmental and genetic factors. To date, more than 200 genetic risk variants, or disease-associated mutations,…

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