Preclinical Study Sheds Light on How Melatonin May Protect Neurons

Preclinical Study Sheds Light on How Melatonin May Protect Neurons

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Preclinical Study Sheds Light on How Melatonin May Protect Neurons

Treatment with melatonin — a hormone best known for its role in sleep regulation — lessened neurodegeneration and motor symptoms in a mouse model of Parkinson’s disease, a study shows. These benefits were associated with the suppression of a death-inducing inflammatory pathway called NLRP3 inflammasome in microglia, the immune cells of the central nervous system (CNS, comprising the brain and spinal cord). The data, which shed light on the mechanisms behind melatonin’s neuroprotective effects, may…

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