Brain-Derived Neurotrophic Factor Levels ‘Unlikely’ as Valid Biomarker

Brain-Derived Neurotrophic Factor Levels ‘Unlikely’ as Valid Biomarker

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Brain-Derived Neurotrophic Factor Levels ‘Unlikely’ as Valid Biomarker

Brain-derived neurotrophic factor (BDNF) may not be the biomarker for Huntington’s disease that it was previously thought to be, a recent study reported. The progressive loss of BDNF, a factor that helps neurons grow and survive, associates with Huntington’s progression in mouse disease models, and past studies found it at reduced levels in patients. Because of this evidence, some experimental Huntington’s therapies target the BDNF pathway. Scientists at University College London, however, recently found no difference in…

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