Motor Neurons From Patients ‘Powerful’ Way of Spotting Therapies

Motor Neurons From Patients ‘Powerful’ Way of Spotting Therapies

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Motor Neurons From Patients ‘Powerful’ Way of Spotting Therapies

Using motor neurons derived from people with amyotrophic lateral sclerosis (ALS) is a promising approach to screen for molecules that prevent certain disease mechanisms, and to identify new targets for therapies, according to a recent study. Two classes of therapies were identified that might lessen the excessive firing of motor neurons in ALS — medications that open the Kv7.2/7.3 potassium channels, and activators of the dopamine D2 receptor. QurAlis is developing an investigational Kv7.2/7.3 activator, called…

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