Tensin 1 Gene Variants May Affect Nutrition in CF Patient Group

Tensin 1 Gene Variants May Affect Nutrition in CF Patient Group

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Tensin 1 Gene Variants May Affect Nutrition in CF Patient Group

Cystic fibrosis (CF) patients with specific variants in the Tensin 1 gene may be at risk of low body mass index (BMI), a measure of nutritional status, if they carry the common CF-causing F508del mutation in both copies of the CFTR gene, a study reports. This makes Tensin 1 (TNS1) a potential modifier gene in CF. A modifier gene is one that can influence disease severity by altering the effects of the underlying disease-causing mutation. The study,…

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