MeCP2 Protein’s Lack May Be Driver of Neuroinflammation in Patients

MeCP2 Protein’s Lack May Be Driver of Neuroinflammation in Patients

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MeCP2 Protein’s Lack May Be Driver of Neuroinflammation in Patients

The lack of a working MeCP2 protein — the most common cause of Rett syndrome — skews the immune system toward a proinflammatory state in the central nervous system (CNS, brain and spinal cord), a study in mice suggests. According to its scientists, this finding helps in understanding the consequences of MECP2 gene mutations on immune function, and may aid in developing new approaches to treat disorders associated with changes in this gene. The study,…

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