Blood-brain Barrier Model May Have Parkinson’s Application

Blood-brain Barrier Model May Have Parkinson’s Application

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Blood-brain Barrier Model May Have Parkinson’s Application

A new human-derived model of the blood-brain barrier (BBB) — a highly selective and protective membrane whose dysfunction is linked to Parkinson’s disease — enables researchers to monitor in detail cellular events upon stress, inflammation, and therapy administration, a study shows. This model allowed the assessment of the protective effects of the antioxidant molecule N-acetylcysteine amide (NACA) against nitrosative stress-induced inflammation thought to contribute to Parkinson’s and other neurodegenerative conditions. The study also showed that BBB breakdown…

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