Rituxan Plus Lower Prednisolone Effective With Fewer Side Effects

Rituxan Plus Lower Prednisolone Effective With Fewer Side Effects

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Rituxan Plus Lower Prednisolone Effective With Fewer Side Effects

Using lower doses of prednisolone in combination with Rituxan (rituximab) resulted in similar rates of remission and fewer adverse events than Rituxan plus higher doses of the glucocorticoid in treating ANCA-associated vasculitis (AAV). Those were the findings of a Phase 4 clinical trial in Japan that examined the effects of high-dose glucocorticoids — which are linked to side effects such as osteoporosis, peptic ulcers, skeletal muscle disorders known as myopathy, and cataracts — versus lower doses…

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