Gut Inflammation Linked to Brain Disease Onset in Preclinical Study

Gut Inflammation Linked to Brain Disease Onset in Preclinical Study

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Gut Inflammation Linked to Brain Disease Onset in Preclinical Study

Gut inflammation could play a critical role in the onset and progression of Parkinson’s disease, a preclinical study shows. Specifically, this type of inflammation triggered the accumulation of alpha-synuclein protein clumps in the nerves lining the colon of a mouse model of Parkinson’s, say scientists from Van Andel Institute in Michigan and Roche Pharma Research in Switzerland. Eventually, disease-causing alpha-synuclein occurred in the brain, leading to the loss of cells that produce dopamine, the underlying…

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