Dopamine Transporter Gene Mutation May Cause Parkinson’s-like Symptoms

Dopamine Transporter Gene Mutation May Cause Parkinson’s-like Symptoms

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Dopamine Transporter Gene Mutation May Cause Parkinson’s-like Symptoms

Structural changes — caused by a rare genetic mutation — to a protein called a dopamine transporter, which conveys dopamine into cells, may contribute to Parkinson’s disease-like symptoms, a study in fruit flies has found. Increasing the number of functional, or properly working, dopamine transporters in fruit flies with the mutation lessened problems with movement coordination, the study found. These findings highlight the benefits of targeting dopamine transporters as a treatment strategy for people with…

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