Small Molecule ISRIB Found to Reduce Scarring in Mouse Models

Small Molecule ISRIB Found to Reduce Scarring in Mouse Models

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Small Molecule ISRIB Found to Reduce Scarring in Mouse Models

Scientists have found a small molecule, called ISRIB, that was able to reduce fibrosis (scarring) and other disease-related features in mice with induced pulmonary fibrosis (PF). ISRIB successfully enhanced the repair process in lung cells that is altered in PF, especially in older mice. According to investigators, these findings support further development of ISRIB as an alternative strategy to treat the condition, which occurs mainly in older people.  The findings were reported in a study,…

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