Nasal Gel Enhances Levodopa Delivery to Brain in Preclinical Study

Nasal Gel Enhances Levodopa Delivery to Brain in Preclinical Study

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Nasal Gel Enhances Levodopa Delivery to Brain in Preclinical Study

Levodopa, a standard treatment for Parkinson’s disease, reached the brain faster when given as a gel into the nasal cavity than as an intravenous (into-the-vein) injection, a new mouse study shows. The findings support the potential of intranasal administration as a way to reach the brain and bypass the breakdown of levodopa by the liver and gut — rendering it less available — when given orally, allowing patients to control their symptoms for longer. The…

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