Repurposed Trifluoperazine (TFP) May Be Effective PAH Therapy

Repurposed Trifluoperazine (TFP) May Be Effective PAH Therapy

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Repurposed Trifluoperazine (TFP) May Be Effective PAH Therapy

Trifluoperazine or TFP, an approved schizophrenia medication, also may be effective in the treatment of pulmonary arterial hypertension (PAH), a preclinical study suggests. In rat models of PAH, trifluoperazine was found to provide therapeutic benefits — without causing detectable side effects. The study, “Preclinical Investigation of Trifluoperazine as a Novel Therapeutic Agent for the Treatment of Pulmonary Arterial Hypertension,” was published in the International Journal of Molecular Sciences. One of the key features of PAH…

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