SMA May Carry Higher Risk of Fluid Buildup in Brain, Study Finds

SMA May Carry Higher Risk of Fluid Buildup in Brain, Study Finds

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SMA May Carry Higher Risk of Fluid Buildup in Brain, Study Finds

Spinal muscular atrophy (SMA) patients may at a fourfold greater risk of hydrocephalus, or abnormal accumulation of cerebrospinal fluid (CSF) in the brain, than their healthy peers, a large U.S. health record-based study suggests. Data also showed that patients younger than 2 years, those most likely to have more severe disease, had the highest incidence of hydrocephalus. This brain condition has been reported in patients treated with Spinraza (nusinersen), which is delivered into the CSF. But these results,…

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