RNA Molecule Appears to Regulate Tau Levels in Brain, Study Says

RNA Molecule Appears to Regulate Tau Levels in Brain, Study Says

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RNA Molecule Appears to Regulate Tau Levels in Brain, Study Says

The production of tau — a protein that forms toxic aggregates in Parkinson’s disease — in the brain is tightly regulated by a small, regulatory RNA molecule called MAPT-AS1, a study reports. Notably, increasing MAPT-AS1 production in the brains of mice significantly reduced tau levels, suggesting that similar approaches might slow disease progression in tau-related neurodegenerative diseases, such as Parkinson’s, Alzheimer’s disease, corticobasal degeneration, and progressive supranuclear palsy. MAPT-AS1 was also found to belong to…

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