Changes in Blood Cell Ratios Linked to Worse Outcomes

Changes in Blood Cell Ratios Linked to Worse Outcomes

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Changes in Blood Cell Ratios Linked to Worse Outcomes

Idiopathic pulmonary fibrosis (IPF) patients showing greater changes in blood cell ratios often used as markers of inflammation are at higher risk of lung function decline, respiratory hospitalization, and death, according to a post-hoc analysis of data from several Phase 3 clinical trials. Notably, these associations were more pronounced in trial participants assigned to a placebo than among those given Esbriet (pirfenidone), suggesting that these blood cell ratios may be less suitable as predictive biomarkers…

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