Researchers Shed Light on Metabolic Profile of Fragile X Mouse Model

Researchers Shed Light on Metabolic Profile of Fragile X Mouse Model

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Researchers Shed Light on Metabolic Profile of Fragile X Mouse Model

A mouse model of fragile X syndrome has higher body weight and distinct metabolic changes relative to healthy mice and mouse models of two other neurodevelopmental disorders, a study shows. The findings highlight not only that each mouse model exhibits a unique, sex-specific metabolic signature, but also that problems in mitochondria, which provide energy to cells, may contribute to three neurodevelopmental disorders: fragile X, Down syndrome, and 16p11.2 deletion syndrome. This adds to the growing…

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