Muscle Weakness Tied to Poor Mitochondria Function

Muscle Weakness Tied to Poor Mitochondria Function

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Muscle Weakness Tied to Poor Mitochondria Function

Poorly working mitochondria — small energy-producing cell compartments — may drive muscle weakness or wasting in a new mouse model of porphyria, a study suggests. “In some cases, muscle atrophy [is] present in porphyria; however, the underlying mechanism is still unknown,” its authors wrote. These findings may therefore provide new insights into the causes of the disease. The study, “Muscle atrophy induced by overexpression of ALAS2 is related to muscle mitochondrial dysfunction,” was published in…

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