Cushing’s Patient With Cortisol ‘Feedback Loop’ May Show New Subtype

Cushing’s Patient With Cortisol ‘Feedback Loop’ May Show New Subtype

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Cushing’s Patient With Cortisol ‘Feedback Loop’ May Show New Subtype

A woman with a rare case of Cushing’s disease, in which rising cortisol triggered the production of yet more cortisol, may represent a new subtype of the disorder. She was the focus of the recent case report “Tumor shrinkage by metyrapone in Cushing’s disease exhibiting glucocorticoid-induced positive feedback,” published in the Journal of the Endocrine Society. The 62-year-old woman was referred to the endocrinology department of a hospital in Japan because of lab tests showing…

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