Genetic Activity in Skin May Define Stages of Juvenile Localized Scleroderma

Genetic Activity in Skin May Define Stages of Juvenile Localized Scleroderma

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Genetic Activity in Skin May Define Stages of Juvenile Localized Scleroderma

Distinct profiles of gene activity in skin samples distinguish different disease stages in juvenile localized scleroderma, a study suggests. These profiles did not necessarily match the patients’ clinical subtype or the disease’s location on the body, suggesting that they may better represent distinct and clinically relevant subgroups of patients, which may be key to predict treatment response and outcomes, its researchers noted. They plan additional studies to assess these profiles’ clinical and predictive values. The…

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