Scientists Identify Molecule That Triggers AAV-related Defense Mechanism

Scientists Identify Molecule That Triggers AAV-related Defense Mechanism

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Scientists Identify Molecule That Triggers AAV-related Defense Mechanism

A molecule released by platelets — cell fragments in the blood that form clots and stop or prevent bleeding — appears to contribute to the progression of ANCA-associated vasculitis (AAV) by triggering a defense mechanism carried out by white blood cells. Researchers now have identified a key signaling event present in that defense mechanism that may help identify new therapeutic targets for use against the autoimmune disorder. Their study, “Platelet CXCL4 mediates neutrophil extracellular traps…

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