YTX-7739 Works to Block SCD Enzyme at Well-Tolerated Doses, Yumanity Says

YTX-7739 Works to Block SCD Enzyme at Well-Tolerated Doses, Yumanity Says

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YTX-7739 Works to Block SCD Enzyme at Well-Tolerated Doses, Yumanity Says

Dose-dependent decreases in targeted fatty acids were seen with YTX-7739, an investigational therapy for Parkinson’s disease, suggesting the medicine engages its therapeutic target, according to the results of a Phase 1a multiple-ascending dose study in healthy volunteers. YTX-7739 is a small molecule designed to enter the brain and block the stearoyl-CoA desaturase (SCD) enzyme, which produces certain fatty molecules thought to mediate the effects of alpha-synuclein — the protein that builds inside nerve cells to toxic…

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