Levels of Neutrophil Elastase May Help Predict Disease Severity in CF

Levels of Neutrophil Elastase May Help Predict Disease Severity in CF

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Levels of Neutrophil Elastase May Help Predict Disease Severity in CF

Levels of neutrophil elastase, a pro-inflammatory enzyme normally released by immune cells known as neutrophils, plus a greater diversity and amount of microbes could drive disease severity in cystic fibrosis (CF), a study in two siblings suggests. The study, Two Siblings Homozygous for F508del-CFTR Have Varied Disease Phenotypes and Protein Biomarkers, was published in the International Journal of Molecular Sciences. Biomarkers in CF include sweat chloride levels, intestinal CFTR channel measures, nasal potential difference, as well…

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