Ocrevus Use Linked to PML in Man, 78, With PPMS, Case Report Says

Ocrevus Use Linked to PML in Man, 78, With PPMS, Case Report Says

292011

Ocrevus Use Linked to PML in Man, 78, With PPMS, Case Report Says

A 78-year-old man with multiple sclerosis (MS) developed the brain infection progressive multifocal leukoencephalopathy (PML) after two years of treatment with Ocrevus (ocrelizumab), a recent case report detailed. Treatment was discontinued and, as the patient’s symptoms worsened, he was moved to off-label treatment with pembrolizumab (a cancer treatment, brand name Keytruda) before he died. While nine other cases of PML have been associated with Ocrevus treatment, each of these patients had switched to Ocrevus from another…

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