2 Pro-inflammatory T-cell Subsets Linked to Disease Severity in Study

2 Pro-inflammatory T-cell Subsets Linked to Disease Severity in Study

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2 Pro-inflammatory T-cell Subsets Linked to Disease Severity in Study

Blood levels of two pro-inflammatory subsets of immune T-cells are abnormally low in people with myasthenia gravis (MG) who have antibodies against the acetylcholine receptor (AChR), a study shows. The reduced levels of these cells were associated with their retention in a patient’s thymus — whose removal is a common MG therapeutic approach — supporting the organ’s role in disease-related abnormal immune attacks. Notably, lower frequencies of both T-cell subsets were associated with high disease…

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