Gene Deficiency in CMTX May Limit Nerve Injury, Mouse Study Suggests

Gene Deficiency in CMTX May Limit Nerve Injury, Mouse Study Suggests

291813

Gene Deficiency in CMTX May Limit Nerve Injury, Mouse Study Suggests

Sciatic motor nerves in mice lacking the GJB1 gene — defective in people with X-linked Charcot-Marie-Tooth (CMTX) disease — regenerated more after external injury than was seen in healthy mice, a study has revealed.  These findings suggested that GJB1 deficiency may provide some protection limiting the impact of additional nerve injury, the scientists said.  The study, “Effects of Early Crush on Aging Wild Type and Connexin 32 Knockout Mice: Evidence for a Neuroprotective State in…

You must be logged in to read/download the full post.