Enzyme Triggers Parkin Protein to Quickly Clear Damaged Mitochondria, Study Finds

Enzyme Triggers Parkin Protein to Quickly Clear Damaged Mitochondria, Study Finds

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Enzyme Triggers Parkin Protein to Quickly Clear Damaged Mitochondria, Study Finds

An enzyme called AMPK drives the clearance of damaged mitochondria, each cell’s energy source, by rapidly promoting the initial activation of the parkin protein — whose deficiency is linked to early onset, hereditary Parkinson’s disease, a study shows. Parkin, which targets defective mitochondria for degradation, a process key to maintaining a cell’s health, was found to be activated within five minutes of mitochondrial damage, scientists report of their discovery of the first steps in cellular response…

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