MeCP Protein’s Ability to Interact With DNA May Be Crucial for Brain Health

MeCP Protein’s Ability to Interact With DNA May Be Crucial for Brain Health

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MeCP Protein’s Ability to Interact With DNA May Be Crucial for Brain Health

MeCP2, the protein missing or defective in most people with Rett syndrome, contains a specific domain it can use to interact with different sets of DNA building blocks found in gene sequences to control their activity. After replacing the protein’s domain to prevent it from binding to a specific set made up of three nucleotides (DNA building blocks) in mice, scientists found signs of what would be a severe form of Rett in the animals,…

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