Balance of Cohesin Proteins Appear Central to X Chromosome Activity

Balance of Cohesin Proteins Appear Central to X Chromosome Activity

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Balance of Cohesin Proteins Appear Central to X Chromosome Activity

A fine balance of proteins called cohesins is important for the normal inactivation of the X chromosome, new research suggests. Better understanding how the activity of the X chromosome activity is regulated could be important for treating conditions like Rett syndrome, which is caused by a mutation in a gene located on the X chromosome. These findings were in the study “Balancing cohesin eviction and retention prevents aberrant chromosomal interactions, Polycomb-mediated repression, and X-inactivation,” published in…

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