Study Finds Poor Mineralization in Teeth of XLH Children

Study Finds Poor Mineralization in Teeth of XLH Children

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Study Finds Poor Mineralization in Teeth of XLH Children

The teeth of children with X-linked hypophosphatemia (XLH) are marked by defects in mineralization affecting the three layers of hard dental tissue — enamel, dentin and cementum — a small study reports. The study, “Mineralization Defects in the Primary Dentition Associated with X-linked Hypophosphatemic Rickets,” was published in the Journal of the American Society for Bone and Mineral Research. XLH is caused by mutations in the PHEX gene that provides instructions for making a protein…

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