MS-linked Molecule IL-17 Impaired Immune Cells in Mice’s Brains

MS-linked Molecule IL-17 Impaired Immune Cells in Mice’s Brains

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MS-linked Molecule IL-17 Impaired Immune Cells in Mice’s Brains

Sustained, excessive levels of interleukin 17A (IL-17A) — a pro-inflammatory molecule linked to multiple sclerosis (MS) and other autoimmune diseases — reduce the number and activity of the brain’s immune cells in the dentate gyrus, according to a study in mice. The dentate gyrus is part of the hippocampus, a brain region with a well-established role in memory. However, no other significant changes were observed in hippocampal cells and function in the mice with chronically high…

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