Progesterone May Help Drive Spread of Ovarian Cancer, Preclinical Study Shows

Progesterone May Help Drive Spread of Ovarian Cancer, Preclinical Study Shows

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Progesterone May Help Drive Spread of Ovarian Cancer, Preclinical Study Shows

The hormone progesterone helps to drive the development of metastatic ovarian cancer, and blocking progesterone signaling may be a useful strategy for preventing the cancer, a study in mice suggests. The study, “Targeting progesterone signaling prevents metastatic ovarian cancer,” was published in PNAS. High-grade serous carcinoma (HGSC) is the most common, and most deadly, form of ovarian cancer. Although considered an ovarian cancer, most HGSC tumors don’t arise from the ovaries themselves, but rather from the…

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