Gene Active in Skeletal Muscle Controls Mice’s Fat Metabolism

Gene Active in Skeletal Muscle Controls Mice’s Fat Metabolism

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Gene Active in Skeletal Muscle Controls Mice’s Fat Metabolism

Skeletal muscle regulates how the body stores and metabolizes fats through the Krüppel-like factor 15 (KLF15) gene, establishing a molecular link between muscle health and conditions such as obesity and diabetes, according to a recent study in mice. The findings also showed that a diet rich in short-chain fatty acids — obtained from fruits, vegetables, beans and whole grains — protected against weight gain and also facilitated weight loss in mice lacking KLF15 in their…

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