A good diet and companionship, or treatment with an antidepressant called duloxetine was seen to significantly lessen pain in a mouse model of sickle cell disease (SCD), a study reports. Notably, each intervention was associated with higher levels in the animals of serotonin, a brain chemical messenger involved in stabilizing mood, feelings of well-being, and happiness. These findings suggest that serotonin-boosting approaches, either psychosocial ones that rely on enriched nutrition and relationships or pharmacological ones involving…

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