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Galapagos Stopping ISABELA Phase 3 Program of Ziritaxestat in Treating IPF

Galapagos and Gilead Sciences have suspended the worldwide ISABELA Phase 3 program investigating the potential of oral ziritaxestat (GLPG1690) to treat people with idiopathic pulmonary fibrosis (IPF). The decision to halt the program, which includes two identical Phase 3 trials — ISABELA 1 (NCT03711162) and ISABELA 2 (NCT03733444) — was based on recommendations of the independent data monitoring committee overseeing the studies. After reviewing data from both trials, the committee concluded that the potential benefits of ziritaxestat…