Darzalex Combos Linked to Stronger Cancer Eradication, Prolonged Survival

Darzalex Combos Linked to Stronger Cancer Eradication, Prolonged Survival

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Darzalex Combos Linked to Stronger Cancer Eradication, Prolonged Survival

Adding Darzalex (daratumumab) to standard regimens for adults with relapsed or refractory multiple myeloma resulted in higher rates of deep and durable responses, according to exploratory analyses of two Phase 3 trials. These findings, from the ongoing POLLUX (NCT02076009) and CASTOR (NCT02136134) trials, were based on patients achieving and sustaining a status of minimal residual disease (MRD) negativity — less than one cancer cell per 100,000 white blood cells — which is associated with prolonged…

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