Early-life Trauma Affects MS Development, Treatment in Mice

Early-life Trauma Affects MS Development, Treatment in Mice

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Early-life Trauma Affects MS Development, Treatment in Mice

Childhood trauma can affect disease progression of multiple sclerosis (MS) and treatment in adulthood, a study in mice suggests. The study shows that mice that experienced early-life trauma were more likely to develop an autoimmune condition and less likely to respond to common treatment with interferon beta. The study, “Early-life-trauma triggers interferon-β resistance and neurodegeneration in a multiple sclerosis model via downregulated β1-adrenergic signaling,” was published in the journal Nature Communications. MS is a progressive,…

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