Suppressing the activity of a cellular transporter called multidrug resistance protein 4 (Mrp4) results in more fat tissue, less energy expenditure, and insulin resistance, according to a study in mice. These findings suggest that lower-than-normal Mrp4 levels can increase the risk of developing metabolic diseases such as obesity and type 2 diabetes, and spot the Mrp4 gene as a new genetic factor of such conditions, researchers said. The study, “Multidrug resistance‐associated protein 4 (Mrp4) is…

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