Genetic Signature May Identify sJIA Children Who Respond to Ilaris

Genetic Signature May Identify sJIA Children Who Respond to Ilaris

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Genetic Signature May Identify sJIA Children Who Respond to Ilaris

A specific genetic signature can help in identifying children with systemic onset juvenile arthritis (sJIA) who are most likely to respond well to Ilaris (canakinumab), a study suggests. Children with a more severe dysregulation of genes associated with signaling cascades involved in the control of immune and inflammatory responses were likely to have strong responses to treatment, the scientists found. But further studies are needed to confirm these observations so they might be of clinical…

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