Scientists at Cognition Therapeutics have found that compounds that are able to dampen the activity of sigma-2 receptors — receptors that are part of a network that controls the destruction of misfolded proteins — are highly effective at preventing molecule trafficking defects driven by the presence of misfolded alpha-synuclein inside neurons. According to researchers, the findings suggest these small molecule compounds may be used one day to fight neurodegeneration driven by the buildup of misfolded alpha-synuclein…

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