Infections Triggering MPO-AAV Should Be Considered in Treatment, Review Suggests

Infections Triggering MPO-AAV Should Be Considered in Treatment, Review Suggests

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Infections Triggering MPO-AAV Should Be Considered in Treatment, Review Suggests

In some cases, infections may trigger the development of ANCA-associated vasculitis (AAV) with antibodies against the myeloperoxidase (MPO) protein, but the condition — known as AAV-MPO — typically regresses after the infection is treated, a systemic review finds. However, the use of immunosuppressive medications to treat the vasculitis may significantly impair the immune system from clearing out the infection. Therefore, infections should be considered in treating patients with MPO-AAV, the findings suggest. The study, “Infection-induced…

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