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Differences in Activity of Various Genes May Drive Scleroderma

Small genetic variations that alter gene activity could play a role in the development of scleroderma and open new avenues for treating the disorder, a study indicates. Many of the genes identified through this work also show unusual levels of activity in tissues often affected in this disease. The study, “eQTL analysis in systemic sclerosis identifies new candidate genes associated with multiple aspects of disease pathology,” was published in the journal Arthritis & Rheumatology. As is…