SERPINA3 Nerve Injury-induced Protein May Be Biomarker of PPMS

SERPINA3 Nerve Injury-induced Protein May Be Biomarker of PPMS

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SERPINA3 Nerve Injury-induced Protein May Be Biomarker of PPMS

People with primary progressive multiple sclerosis (PPMS) have significantly higher levels of a nerve injury-induced protein, called SERPINA3, in the cerebrospinal fluid (CSF) than do those with relapsing-remitting MS (RRMS) and those without the neurodegenerative disease, a study shows. Of note, the CSF is the liquid that bathes the central nervous system (CNS), composed of the brain and spinal cord. In addition, SERPINA3 CSF levels were associated with those of neurofilament light (NfL), a biomarker…

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