Cancer Found After Death of LEMS Patient with Rare Immune-mediated Disorder

Cancer Found After Death of LEMS Patient with Rare Immune-mediated Disorder

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Cancer Found After Death of LEMS Patient with Rare Immune-mediated Disorder

A positive SOX1 antibody test led to a post-mortem small-cell lung carcinoma (SCLC) diagnosis in a man with paraneoplastic cerebellar degeneration (PCD) and Lambert-Eaton myasthenic syndrome (LEMS), a case study reports. “To our knowledge, this is the first reported case of PCD-LEMS with positive SOX-1 antibodies,” the investigators wrote, adding that the case highlights the importance of SCLC evaluation in patients with PCD-LEMS and SOX1 antibodies. The case report, “Paraneoplastic Cerebellar Degeneration and Lambert-Eaton Myasthenic…

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