Ocrevus Targets Pro-inflammatory T-cells, Not Just B-cells, in PPMS, Study Finds

Ocrevus Targets Pro-inflammatory T-cells, Not Just B-cells, in PPMS, Study Finds

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Ocrevus Targets Pro-inflammatory T-cells, Not Just B-cells, in PPMS, Study Finds

In addition to significantly reducing subsets of B-cells — its main immune cell target — Ocrevus (ocrelizumab) lessens pro-inflammatory immune T-cells in people with primary progressive multiple sclerosis (PPMS), a small study shows. Notably, the suppression of immune cell subsets thought to be involved in the abnormal immune responses seen in MS patients was accompanied by a clear drop in the levels of serum neurofilament light chain (sNfL), a biomarker of nerve cell damage. These findings…

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