Trim28 Gene Implicated in Fat Storage, Obesity, Mouse Study Reports

Trim28 Gene Implicated in Fat Storage, Obesity, Mouse Study Reports

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Trim28 Gene Implicated in Fat Storage, Obesity, Mouse Study Reports

Deleting a gene called Trim28 in mice led to alterations in fat storage and metabolism, especially in female mice, who became significantly heavier, a study reported. These findings demonstrate Trim28‘s role in genetic obesity and show that the gene may be a potential target for the prevention and treatment of obesity.  The study, “Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance,” was published in the journal Nature Communications.  Fat (lipid) intake…

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