Compound That Mimics Thyroid Hormone Prevents MS Nerve Damage in Mice

Compound That Mimics Thyroid Hormone Prevents MS Nerve Damage in Mice

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Compound That Mimics Thyroid Hormone Prevents MS Nerve Damage in Mice

A thyroid hormone-mimicking compound not only prevented nerve cell damage but promoted the cells’ survival in a mouse model of multiple sclerosis (MS). This discovery advances previous research showing that the compound, called sobetirome, can induce the repair of myelin, the protective sheath around nerves. The data suggest that thyromimetics — molecules that mimic the thyroid hormone — could form the basis of a therapeutic strategy to prevent the progression of MS and other neurodegenerative…

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