CD46 Mutation Not Enough to Trigger aHUS, Genetic Analysis Shows

CD46 Mutation Not Enough to Trigger aHUS, Genetic Analysis Shows

282874

CD46 Mutation Not Enough to Trigger aHUS, Genetic Analysis Shows

A common mutation in the CD46 gene associated with atypical hemolytic uremic syndrome (aHUS) onset does not seem to be enough to trigger the disorder, as it occurs in both affected and unaffected family members, a genetic analysis shows.  Further analysis found evidence of an unknown factor circulating in the blood of a male patient that, when combined with the CD46 mutation, caused aHUS. The researchers said their findings “highlight the complexity” of the genetics…

You must be logged in to read/download the full post.