Targeting Calcium‐sensing Receptor May Help Slow Disease Progression

Targeting Calcium‐sensing Receptor May Help Slow Disease Progression

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Targeting Calcium‐sensing Receptor May Help Slow Disease Progression

Targeting the calcium‐sensing receptor (CaSR), which plays a critical role in the development of bone cells, may be a therapeutic strategy to slow the progression of ankylosing spondylitis (AS), a study suggests. The study, “Aberrant upregulation of CaSR promotes pathological new bone formation in ankylosing spondylitis,” was published in the journal EMBO Molecular Medicine. AS is a form of arthritis that primarily affects the joints of the spine. Patients may develop ankylosis, which results from…

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